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亞洲抗衰老協會

Biochemical, Immunological, Hormonal and Anti-Oxidant Effects of a Chinese Herbal Suppository, Vigconic VI-28, on Elderly Male Subjects An Anti-ageing Solution?





Biochemical, Immunological, Hormonal and Anti-Oxidant Effects of a Chinese Herbal Suppository, Vigconic VI-28, on Elderly Male Subjects An Anti-ageing Solution?


S. H. Chui , K. M. Ko

Asia Anti-Aging Association, Hong Kong, China, and Department of

Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China


Ageing is usually defined as the progressive loss of function accompanied by decreasing fertility and increasing mortality with advancing age . It is believed that the holistic approach in the practice of Traditional Chinese Medicine (TCM) can slow down the ageing process. We have studied the effect of a Chinese herbal suppository, Vigconic VI-28 (mainly containing Radix Ginseng, Cornu Cervi Pantotrichum, Cordyceps, Radix Salviae Miltiorrhizae, Tuber Onion Seed, Fructus Cnidii, Fructus Evodiae, Rhizoma Kaempseriae), on 25 healthy male subjects aged from 51 to 66 (mean = 55.4) for 12 weeks. All subjects were examined by Western medicine and Chinese medicine practitioners separately at one-month interval, with blood specimens being taken at each clinic visit for assessing biochemical, immunological, hormonal and anti-oxidant markers. Over 18 subjects (or 75%) indicated an increased libido and improved stamina, or a reduced frequency of urination during night time. No obvious adverse effects on liver function, renal function and haematological status were observed.


The data (mean, n=25) are shown as follows:



Week 0

Week 4

Week 12

P value

HDL-cholesterol (mmol/L)

1.20

1.27

1.37 *

P < 0.001

Total Chol./HDL- chol.

4.54

4.30 *

4.39

P < 0.01

Cortisol (a.m.) (g/dL)

17.2

13.6

11.9 *

P = 0.001

Insulin-like growth factor - 1 (ng/mL)

188

211

248 *

P = 0.001

CD4 (cell count/l)

535.7

777.9 *

373.4

P < 0.001

CD8 (cell count/l)

376.6

471.4 *

412.0

P = 0.01

RBC Cu Zn SOD (U/mg Hb)

1.19

1.42

1.94 *

P < 0.001

Plasma DPPH scavenging eq. (mol/ml)

0.50

0.55

0.61 *

P < 0.05

* statistically significant when compared with Week 0; No specimen was taken at Week 8


We conclude that Vigconic VI-28 has the potential of improving vigor and slowing down the ageing process through modulating cholesterol metabolism, regulating hormonal status and enhancing body immunity, as well as elevating blood anti-oxidant status.


Acknowledgements:

We thank Vigconic (International) Ltd. for the sponsorship, Dr. W.C. Yam of The University of Hong Kong for CD4 and CD8 studies, and Dr. Robert M.T. Chan of The University of Hong Kong for clinical examination of the subjects in the study.


酪BL Kirkland and SN Austad. Why do we age? Nature 408; 233-238, 2000









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